Pure-grade ammonium acetate finds applications in various fields due to its properties. Some common uses include:

1. Buffer Solution: Ammonium acetate is commonly used as a buffer in biochemical and molecular biology applications. Its ability to maintain a stable pH makes it useful in reactions and experiments where maintaining a specific pH range is crucial.
2. Chemical Synthesis: Pure-grade ammonium acetate serves as a reagent in chemical synthesis, particularly in organic chemistry. It can be used in reactions to form other acetates or as a precursor for various organic compounds.
3. Mass Spectrometry: Ammonium acetate is employed as a volatile buffer in mass spectrometry techniques. It helps in the ionization of analytes, aiding in the detection and analysis of compounds. It is often used in the analysis of small molecules, peptides, and proteins.
4. DNA and RNA Precipitation: Ammonium acetate is utilized in molecular biology for DNA and RNA precipitation. When combined with alcohol, it helps to selectively precipitate nucleic acids, allowing their separation from other cellular components.
5. pH Adjustment: Due to its acidic properties, ammonium acetate can be used to adjust the pH of solutions. It is particularly useful in applications where a slightly acidic environment is desired.
6. Food Additive: Ammonium acetate is approved as a food additive by regulatory authorities. It is used in some food products as an acidity regulator, flavouring agent, or preservative.
7. Agriculture: In agriculture, ammonium acetate is sometimes used as a nitrogen source in fertilizers. It provides plants with essential nutrients for growth and development.

It’s important to note that while ammonium acetate is generally considered safe for its intended uses, proper handling and safety precautions should always be followed, and specific regulations and guidelines should be consulted depending on the particular application.